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- Albert Einstein-

“The process of scientific discovery is, in effect,

a continual flight from wonder.”

PUBLICATIONS

Journal Publications
  • Jun Kim, Bo-Bae Seo, Ki Hyun Hong, Sung Eun Kim, Young-Min Kim, Soo-Chang Song, Long-Term Anti-Inflammatory Effects of Injectable Celecoxib Nanoparticle Hydrogels for Achilles Tendon Regeneration, Acta Biomaterialia, 2022

  • Bo-Bae Seo, Youngjoong Kwon, Jun Kim, Ki Hyun Hong, Sung-Eun Kim, Hae-Ryong Song, Young-Min Kim, Soo-Chang Song, Injectable polymeric nanoparticle hydrogel system for long-term anti-inflammatory effect to treat osteoarthritis, Bioactive Materials, 2022, 7, 14-25

  • Muhammad Suhaeri, Young-Min Kim, Rika Tri Yunarti, Soo Chang Song, Thermoresponsive and suspension forming cyclotriphosphazene conjugate for delivery vehicle of antitumor drug camptothecin, J. Drug Deliv. Sci. Technol., 2021, 102049 

  • Zhang ZQ, Young-Min Kim, Soo Chang Song, Injectable and quadruple-functional hydrogel as an alternative to intravenous delivery for enhanced tumor targeting, ACS Appl. Mater. Interfaces, 2019, 11(38), 34634.

  • Ki Hyun Hong, Young-Min Kim, Soo Chang Song, Fine‐Tunable and Injectable 3D Hydrogel for On‐Demand Stem Cell Niche, Adv. Sci, 2019, 1900597

  • Ki Hyun Hong, Soo Chang Song, 3D hydrogel stem cell niche controlled by host-guest interaction affects stem cell fate and survival rate, Biomaterials, 2019, 218, 119338

  • Bo-Bae Seo, Mi-Ran Park, Soo Chang Song, Sustained Release of Exendin 4 Using Injectable and Ionic-Nano-Complex Forming Polymer Hydrogel System for Long-Term Treatment of Type 2 Diabetes Mellitus, ACS Appl. Mater. Interfaces, 2019, 11, 15201−15211

  • Yeon Su Choi, Kyoungnam Kim, Kitae Ryu, Hana Cho, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Byung Gon Kim, Soo Chang Song, Han Chang Kang, Dual-functionalized calcium nanocomplexes for transfection of cancerous and stem cells: Low molecular weight polycation-mediated colloidal stability and ATP-mediated endosomal release, Journal of Industrial and Engineering Chemistry, 2018, 64(25), 300-10.

  • Bo‐Bae Seo, Hae‐Im Chang, Hyuck Choi, Jeong‐Tae Koh, Kwi‐Dug Yun, Jae‐Yeol Lee, Soo‐Chang Song, New approach for vertical bone regeneration using in situ gelling and sustained BMP‐2 releasing poly(phosphazene) hydrogel system on peri‐implant site with critical defect in a canine model, Journal of Biomedical Materials Research, 2018, 106(2), 751-9.

  • Le Thi Anh Hong, Young-Min Kim, Hee Hwan Park, Dong Hoon Hwang, Yuexian Cui, Eun Mi Lee, Stephanie Yahn, Jae K. Lee, Soo-Chang Song & Byung Gon Kim, An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling, Nature Communications 8, Article number: 533, 2017

  • Zhang ZQ, Song SC, Multiple hyperthermia-mediated release of TRAIL/SPION nanocomplex from thermosensitive polymeric hydrogels for combination cancer therapy, Biomaterials. 2017 Mar 30;132:16-27

  • Seo BB, Chang HI, Choi H, Koh JT, Yun KD, Lee JY, Song SC, New approach for vertical bone regeneration using in situ gelling and sustained BMP-2 releasing poly(phosphazene) hydrogel system on peri-implant site with critical defect in a canine model, Biomed Mater Res B Appl Biomater, 2017, Mar 23

  • Bo-Bae Seo, Jeong-Tae Koh, Soo-Chang Song, Tuning physical properties and BMP-2 release rates of injectable hydrogel systems for an optimal bone regeneration effect, Biomaterials, 2017, 122, 91-104

  • Young-Min Kim, Thrimoorthy Potta, Keun-Hong Park, Soo-Chang Song, Temperature responsive chemical crosslinkable UV pretreated hydrogel for application to injectable tissue regeneration system via differentiations of encapsulated hMSCs, Biomaterials, 2017, 112, 248-256

  • Zhi-Qiang Zhang, Soo-Chang Song, Thermosensitive/superparamagnetic iron oxide nanoparticle-loaded nanocapsule hydrogels for multiple cancer hyperthermia, Biomaterials, 2016, 106, 13-23

  • Young-Min Kim, Chang-Ho Kim, Soo-Chang Song, Injectable Ternary Nanocomplex Hydrogel for Long-Term Chemical Drug/Gene Dual Delivery, ACS Macro Letters, 2016, 5, 297-300

  • Jeong BC, Choi H, Hur SW, Kim JW, Oh SH, Kim HS, Song SC, Lee KB, Park KB, Koh JT, Repair of Cranial Bone Defects Using rhBMP2 and Submicron Particle of Biphasic Calcium Phosphate Ceramics with Through-Hole., Biomed Research International, 2015, Article ID 926291, 9 pages

  • Bo-Bae Seo, Hyuck Choi, Jeong-Tae Koh, Soo-Chang Song, Sustained BMP-2 delivery and injectable bone regeneration using thermosensitive polymeric nanoparticle hydrogel bearing dual interactions with BMP-2, Journal of Controlled Release (Cover), 2015, 209, 67-76

  • Kim YM, Song SC, Targetable micelleplex hydrogel for long-term, effective, and systemic siRNA delivery, Biomaterials, 2014, 35(27), 7970-77

  • Cho JK, Hong JM, Han T, Yang HK, Song SC, Injectable and biodegradable poly(organophosphazene) hydrogel as a delivery system of docetaxel for cancer treatment, Journal of Drug Targeting, 2013, 21(6), 564-573

  • Kim YM, Park MR, Song SC, An injectable cell penetrable nano-polyplex hydrogel for localized siRNA delivery, Biomaterials, 2013, 34(18), 4493-4500

  • Kim JH, Lee JH, Kim KS, Na K, Song SC, Lee J, Kuh HJ, Intratumoral delivery of paclitaxel using a thermo sensitive hydrogel in human tumor xenografts, Archives of Pharmacal Research, 2013, 36(1), 94-101

  • Mi-Ran Park, Bo-Bae Seo, soo-Chang Song, Dual ionic interaction system based on polyelectrolyte complex and ionic, injectable, and thermosensitive hydrogel for sustained release of human growth hormone, Biomaterials, 2013, 34(4), 1327-1336

  • Kim YM, Park MR, Song SC, Injectable Polyplex Hydrogel for Localized and Long-Term Delivery of siRNA, ACS nano, 2012, 6(7), 5757-66

  • Cho JK, Chun C, Kuh HJ, Song SC, Injectable poly(organophosphazene)-camptothecin conjugate hydrogels: Synthesis, characterization, and antitumor activities, Eur J Pharm Biopharm, 2012, 81(3), 582-90

  • Cho JK, Park JW, Song SC, Injectable and biodegradable poly(organophosphazene) gel containing silibinin: its physicochemical properties and anticancer activity, Journal of Pharmaceutical Science, 2012, 101(7), 2382-91

  • Kim JI, Kim B, Chun C, Lee SH, Song SC, MRI-monitored long-term therapeutic hydrogel system for brain tumors without surgical resection, Biomaterials, 2012, 33(19), 4836-42

  • Lee JH, Na K, Song SC, Lee J, Kuh HJ, The distribution and retention of paclitaxel and doxorubicin in multicellular layer cultures, Oncol Rep, 2012, 27(4), 995-1002

  • Kim JI, Lee BS, Chun C, Cho JK, Kim SY, Song SC, Long-term theranostic hydrogel system for solid tumors, Biomaterials, 2012, 33(7), 2251-9

  • Jang Il Kim, ChangJu Chun, Bora Kim, Ji Min Hong, Jung-Kyo Cho, Seung Hoon Lee, Soo-Chang Song, Thermosensitive/magnetic poly(organophosphazene) hydrogel as a long-term magnetic resonance contrast platform, Biomaterials, 2012, 33(1), 218-24

  • Bo-Bae Seo, Mi-Ran Park, ChangJu Chun, Jae-Yeol Lee, Soo-Chang Song, The biological efficiency and bioavailability of human growth hormone delivered using injectable, ionic, thermosensitive poly(organophosphazene)-polyethylenimine conjugate hydrogels, Biomaterials, 2011, 32(32), 8271-80

  • Potta T, Chun C, Song SC, Controlling the Degradation Rate of Thermoresponsive Photo-Cross-linked Poly(organophosphazene) Hydrogels with Compositions of Depsipeptide and PEG Chain Lengths, Polymer Degradation and Stability, 2011, 96, 1261

  • Jung-Kyo Cho, Sun Mi Lee, Chang Won Kim, Soo-Chang Song, Synthesis and characterization of biodegradable
    thermosensitive neutral and acidic poly(organophosphazene)gels bearing carboxylic acid group, Journal of Polymer Research, 2011, 18(4), 701-713

  • Potta T, Chun C, Song SC, Design of Polyphosphazene Hydrogels with Improved Structural Properties by Use of Star-Shaped Multithiol Crosslinkers, Macromol Biosci, 2011, 11(5), 689-99

  • Jung-Kyo Cho, Ki-Yun Hong, Jung Won Park, Han-Kwang Yang, Soo-Chang Song, Injectable delivery system of 2-methoxyestradiol for breast cancer therapy using biodegradable thermosensitive poly(organophosphazene) hydrogel, Journal of Drug Targeting, 2011, 19(4), 270-280

  • Byun Y, Oh YK, Senter PD, Song SC, Meeting Report: International Symposium on Intelligent Drug Delivery Systems, Mol Pharm, 2010, 7(6), 2310-2311

  • Bae Hoon Lee, Soo-Chang Song, Synthesis and Characterization of Thermosensitive Poly(organophosphazene) Gels with an Amino Functional Group, J Appl Polym Sci, 2010, 120(2), 998-1005

  • Jieun Yu, Hyuk-Joon Lee, Keun Hur, Mi Kyung Kwak, Tae Su Han, Woo Ho Kim, Soo-Chang Song, Kazuyoshi Yanagihara and Han-Kwang Yang, The antitumor effect of a thermosensitive polymeric hydrogel containing paclitaxel in a peritoneal carcinomatosis model, Investigational new drugs,

  • Thrimoorthy Potta, ChangJu Chun, Soo-Chang Song, Rapid Photocrosslinkable Thermoresponsive Injectable Polyphosphazene Hydrogels, Macromol Rapid Comm, 2010, 31(24), 2133-2139

  • Mi-Ran Park, ChangJu Chun, Sung-Won Ahn, Min-Hyo Ki, Chong-Su Cho, Soo-Chang Song, Sustained Delivery of Human Growth Hormone Using a Polyelectrolyte Complex-Loaded Thermosensitive Polyphosphazene Hydrogel, Journal of Controlled Release, 2010, 147, 359-367

  • Thrimoorthy Potta, ChangJu Chun, Soo-Chang Song, Injectable, dual cross-linkable polyphosphazene blend hydrogels, Biomaterials, 2010, 31(32), 8107-20

  • Mi-Ran Park, ChangJu Chun, Chong-Su Cho, Soo-Chang Song, Enhancement of Sustained and Controlled Protein Release Using Polyelectrolyte Complex Loaded Injectable and Thermosensitive Hydrogel, European Journal of Pharmaceutics and Biopharmaceutics, 2010, 76, 179-188

  • Thrimoorthy Potta, ChangJu Chun, Soo-Chang Song, Dual Cross-Linking Systems of Functionally Photo-Cross-Linkable and Thermoresponsive Polyphosphazene Hydrogels for Biomedical Applications, Biomacromolecules, 2010, 11(7), 1741-53

  • Hu-Lin Jiang, You-Kyoung Kim, Sun-Mi Lee, Mi-Ran Park, Eun-Mi Kim, Yong-Mei Jin, Rohidas Arote,
    Hwan-Jeong Jeong, Soo-Chang Song, Myung-Haing Cho, and Chong-Su Cho, Galactosylated Chitosan-g-PEI/DNA Complexes-loaded Poly(organophosphazene) Hydrogel as a Hepatocyte Targeting Gene Delivery System, Archives of Pharmacal Research, 2010, 33, 551-556

  • Mi-Ran Park, Chong-Su Cho, Soo-Chang Song, In vitro and in vivo degradation behaviors of thermosensitive
    poly(organophosphazene) hydrogels, Polymer Degradation and Stability, 2010, 95, 935-944

  • Yong Woo Cho, Minyoung Choi, Kyunghae Lee, Soo-Chang Song, Cyclotriphosphazene-Pt-DACH Conjugates with Dipeptide Spacers for Drug Delivery Systems, Journal of Bioactive and Compatible Polymers, 2010, 25 (4), 274-291

  • Al-Abd AM, Hong KY, Song SC, Kuh HJ, Pharmacokinetics of Doxorubicin after Intratumoral Injection using a Thermosensitive Hydrogel in Tumor-bearing Mice, Journal of Controlled Release, 2010, 142, 101-107

  • Mi-Ran Park, ChangJu Chun, Sung-Won Ahn, Min-Hyo Ki, Chong-Su Cho, Soo-Chang Song, Cationic and thermosensitive protamine conjugated gels for enhancing sustained human growth hormone delivery, Biomaterials, 2010, 31, 1349-1359

  • Mi kyung Kwak, Keun Hur, Ji Eun Yu, Tae Su Han, Kazuyoshi Yanagihara, Woo Ho Kim, Sun Mi Lee, Soo-Chang Song, Han-Kwang Yang, Suppression of in vivo tumor growth by using a biodegradable thermosensitive hydrogel polymer containing chemotherapeutic agent, Investigational new drugs, 2010, 28, 284-290

  • Oh YK, Senter PD, Song SC, Intelligent Drug Delivery Systems, Bioconjugate Chem, 2009, 20 (10), 1813-1815

  • ChangJu Chun, Hye Jin Lim, Ki-Yun Hong, Keun-Hong Park, Soo-Chang Song, The use of injectable, thermosensitive poly(organophosphazene)–RGD conjugates for the enhancement of mesenchymal stem cell osteogenic differentiation, Biomaterials, 2009, 30, 6295-6308

  • Thrimoorthy Potta, ChangJu Chun, Soo-Chang Song, Chemically crosslinkable thermosensitive polyphosphazene gels
    as injectable materials for biomedical applications, Biomaterials, 2009, 30, 6178-6192

  • Chun C, Lee SM, Kim CW, Hong KY, Kim SY, Yang HK, Song SC, Doxorubicin-polyphosphazene conjugate hydrogels for locally controlled delivery of cancer therapeutics, Biomaterials, 2009, 30(27), 4752-62

  • Chun C, Lee SM, Kim SY, Yang HK, Song SC, Thermosensitive poly(organophosphazene)-paclitaxel conjugate gels for antitumor applications, Biomaterials, 2009, 30, 2349-2360 

  • Ahmed M. Al-Abd, Nam Ho Kim, Soo-Chang Song, Seung Jin Lee and Hyo-Jeong Kuh, A simple HPLC method for doxorubicin in plasma and tissues of nude mice, Archives of Pharmacal Research, 2009, 32(4), 605-611

  • Sun Mi Lee, Chang Ju Chun, Jeong Yun Heo, Soo-Chang Song, Injectable and thermosensitive poly(organophosphazene) hydrogels for a 5-fluorouracil delivery, Journal of Applied Polymer Science, 2009, 113(6), 3381-2289 

  • Sungsook Ahn, Sung Won Ahn, Soo-Chang Song, Thermothickening modification of the poly(ethylene glycol) and amino acid ester grafted polyphosphazenes by monomethyl end-capped poly(ethylene glycol) addition, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2009, 333(1-3), 82-90

  • Ahn S, Monge EC, Song SC, Ion and pH Effect on the Lower Critical Solution Temperature Phase Behavior in Neutral and Acidic Poly(organophosphazene) Counterparts, Langmuir, 2009, 25 (4), 2407–2418

  • Sungsook Ahn, Sung Won Ahn, Soo-Chang Song, Thermosensitive amphiphilic polyphosphazenes and their interaction with ionic surfactants, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2008, 330(2-3), 184-192

  • Sungsook Ahn, Sung Won Ahn, Soo-Chang Song, Polymer structure-dependent ion interaction studied by amphiphilic nonionic poly(organophosphazenes), Journal of Polymer Science Part B: Polymer Physics, 2008, 46(19), 2022-2034

  • Oh YK, Senter PD, Song SC, Meeting Report: International Symposium on Intelligent Drug Delivery Systems South Korea, 2008, Molecular pharmaceutics, 2008

  • Kang GD, Song SC, Effect of chitosan on the release of protein from thermosensitive poly(organophosphazene) hydrogels, International Journal of Pharmaceutics, 2008, 349(1-2), 188-95

  • Park MR, Kim HW, Hwang CS, Han KO, Choi YJ, Song SC, Cho MH, Cho CS, Highly efficient gene transfer with degradable poly(ester amine) based on poly(ethylene glycol) diacrylate and polyethylenimine in vitro and in vivo, The Journal of gene medicine, 2008, 10(2), 198-207

  • Yoon JY, Park KH, Song SC, A thermosensitive poly(organophosphazene) hydrogel for injectable tissue-engineering applications, Journal of biomaterials science. Polymer edition, 2007, 18(9), 1181-93

  • Hoffman AS et al, International Symposium on Intelligent Drug Delivery Systems, AAPS PharmSciTech, 2007, 8(2), Article 49

  • Gyung D. Kang, Se H. Cheon, Soo-Chang Song, Controlled release of doxorubicin from thermosensitive poly(organophosphazene) hydrogels, International Journal of Pharmaceutics, 2006

  • Gyung Don Kang, Se Hwa Cheon, Gilson Khang, Soo-Chang Song, Thermosensitive poly(organophosphazene) hydrogels for a controlled drug delivery, European Journal of Pharmaceutics and Biopharmaceutics, 2006, 63, 340–346

  • Keun-Hong Park and Soo Chang Song,

    Morphology of Spheroidal Hepatocytes within Injectable, Biodegradable, and Thermosensitive Poly(organophosphazene) Hydrogel as Cell Delivery Vehicle, Journal of Bioscience and Bioengineering, 2006, 101(3),
    238–242

  • Sung Bum Jung, Gyung Don Kang, Jung Yun Huh, Sungsook Ahn, Estela C. Monge, Gilson Khang,
    Soo-Chang Song, Thermosensitive Biodegradable Poly(organophosphazene) Gels and Their Blends, Tissue Engineering and Regenerative Medicin, 2006, 3(2), 108–113

  • Yong Woo Cho,Sung Won An, Soo-Chang Song, Effect of Inorganic and Organic Salts on the Thermogelling Behavior of Poly(organophosphazenes), Macromol. Chem. Phys, 2006, 207, 412–418

  • Yong Woo Cho, Jeong-Ryel Lee, and Soo-Chang Song, Novel Thermosensitive 5-Fluorouracil-Cyclotriphosphazene
    Conjugates: Synthesis, Thermosensitivity, Degradability, and in Vitro Antitumor Activity, Bioconjugate Chem., 2005, 16, 1529-1535

  • Keun-Hong Park, Soo-Chang Song, A thermo-sensitive poly(organophosphazene) hydrogel used as an extracellular matrix for artificial pancreas, J. Biomater. Sci. Polymer Edn, 2005, 16, 11, 1421–1431

  • Gyung Don Kang, Jeong-Yun Heo, Sung Bum Jung, Soo-Chang Song, Controlling the Thermosensitive Gelation Properties of Poly(organophosphazenes) by Blending, Macromol, 2005, 26, 1615–1618

  • Sang Beom Lee, Soo-Chang Song, Hydrolysis-improved thermosensitive polyorganophosphazenes with α-amino-ω-methoxy-poly(ethylene glycol) and amino acid esters as side groups, Polymer International, 2005, 54,1225–1232

  • Yu Seok Youn, Dong Hee Na, Sun Dong Yoo, Soo-Chang Song, Kang Choon Lee, Carbohydrate-specifically polyethylene glycol-modified ricin A-chain with improved therapeutic potential, The International Journal of
    Biochemistry & Cell Biology, 2005, 37, 1525–1533

  • Yu Seok Youn, Dong Hee Na, Sun Dong Yoo, Soo-Chang Song, Kang Choon Lee, Chromatographic separation and mass spectrometric identification of positional isomers of polyethylene glycol-modified growth hormone-releasing factor (1-29), Journal of Chromatography A, 2004, 1061,45–49

  • B. H Lee and S. C. Song, Synthesis and characterization of biodegradable thermosensitive poly(organophosphazene) Gel, Macromolecules, 2004, 37, 4533

  • S. B. Lee, B. H Lee, H. W. Ha, K. T. Lee, Y. S. Sohn, and S. C. Song, Synthesis and antitumor activity of novel thermosensitive platinum(II)-cyclotriphosphazene conjugates, Journal of Controlled Release, 2003, 90, 303

  • S. B. Lee, Y. S. Sohn, and S. C. Song, Saccharide effect on the lower critical solution temperature of Poly(organophosphazenes) with methoxy-poly(ethylene glycol) and amino acid esters as side groups, Bull. Korean Chem. Soc., 2003, 24, 9001

  • B. H Lee, J. S. Park, and S. C. Song,

    Synthesis and biocompatibility of thermosensitive poly(organophosphazene) gels, Biomaterials Research, 2003, 7, 182

  • B. H Lee and S. C. Song, Biodegradable thermosensitive poly(organophosphazene) hydrogels, Macromol. Chem. Symp, 2003, 16, 56

  • K. H. Park, S. C. Song, T. Akaike, Determination of the specific interaction between sulfonylurea-incorporated
    polymer and rat islets, J. Biochemistry, 2002, 131, 359

  • B. H Lee, Y. M. Lee, Y. S. Sohn, and S. C. Song, Thermosensitive and Hydrolysis-sensitive Poly(organophosphazenes), Polymer Int., 2002, 51, 658

  • B. H Lee and S. C. Song, Synthesis and hydrolytic properties of thermosensitive poly(organophosphazenes), Macromol. Chem. Symp., 2002, 15, 55

  • B. H Lee, Y. M. Lee, Y. S. Sohn, and S. C. Song, A Thermosensitive Poly(organophosphazene) Gel, Macromolecules, 2002, 35, 3876

  • B. H. Lee, Y. M. Lee, Y. S. Sohn, and S. C. Song, Synthesis and Characterization of Thermosensitive Poly(organophosphazenes) with Methoxy-Poly(ethylene glycol) and Alkyl Amines as Side Groups, Bull. Korean Chem. Soc., 2002, 23, 549

  • S. B. Lee, S. C.Song, J. I. Jin, and Y. S. Sohn, Structural and thermosensitive properties of cyclotriphosphazenes with poly(ethylene glycol) and amino acid esters as side groups, Macromolecules, 2001, 34, 7565

  • S. B. Lee, S. C. Song, J. I. Jin, and Y. S. Sohn, Solvent effect on the lower critical solution temperature of biodegradable thermosensitive poly(organophosphazenes), Polymer Bulletin, 2001, 45, 389

  • S. B. Lee, S. C.Song, and Y. S. Sohn, Synthesis and characterization of thermosensitive cyclotriphosphazenes, Macromol. Chem. Symp, 2001, 14, 32

  • S. B. Lee, S. C. Song,J. I. Jin, and Y. S. Sohn, Thermosensitive Cyclotriphosphazenes, J. Am. Chem. Soc., 2000, 122, 8315

  • S. B. Lee, S. C. Song,J. I. Jin, and Y.S. Sohn, Surfactant effect on the lower critical solution temperature of
      poly(organophosphazenes) with methoxy-poly(ethylene glycol) and amino acid esters as side groups, Colloid & Polymer Sci., 2000, 278, 1097

  • S. C. Song, S. B. Lee, J. I. Jin, Y. S. Sohn, A new class of biodegradable thermosensitive polymers. I. Synthesis
    and characterization of poly(organophosphazenes) with methoxy-poly(ethylene glycol) and   amino acid esters as side groups, Macromolecules, 1999, 32, 2188

  • S.B. Lee, S.-C.  Song, J.-I. Jin, and Y.S. Sohn, A new class of biodegradable thermosensitive polymers. 2. Hydrolytic properties and   salt effect on the lower critical solution temperature of poly(organophosphazenes)   with methoxypoly(ethylene glycol) and amino acid esters as side groups, Macromolecules, 1999, 32, 7820

  • S.-C. Song,   C.O. Lee,Y.S. Sohn, A novel polymeric conjugate carrying two different anticancer drugs, Polymer International, 1999

  • S.B. Lee, S.-C. Song, J.-I. Jin, and Y.S.   Sohn, Synthesis and antitumor activity of polyphosphazene/methoxy-poly(ethylene    glycol)/(diamine)platinum(II) conjugates, Polymer Journal, 1999, 31, 1247

  • S.-C. Song, C.O. Lee, and Y.S. Sohn, Synthesis and antitumor activity of poly(organophosphazene)/doxorubicin conjugates, Bull. Korean Chem. Soc., 1999, 20, 250

  • Uchio, M. Baudys, F. Liu, S.C. Song, S.W. Kim, Site-specific insulin conjugates with enhanced stability and extented action profile, Advanced Drug Delivery Reviews, 1999, 35,  289

  • S.-C. Song and Y.S. Sohn, Synthesis and hydrolytic properties of polyphosphazene/(diamine)platinum/saccharide conjugates, Journal of Controlled Release, 1998, 55, 161

  • K.M. Kim, S.-C. Song, S.B. Lee, H.C. Kang,   and Y.S. Sohn, Structural properties of silver(I) and mercury(II) complexes of D-lactobionate:    self-assembled coordination polymers, Inorganic Chemistry, 1998, 37, 5764

  • A, F. Liu, S.-C. Song, D. Mix, M. Baudys, and S.W. Kim, Glucose-induced release of glycosylpoly(ethylene glycol) insulin bound to a soluble   conjugtae of concanavalin, Bioconjugate chemistry, 1997, 8, 664

  • T. Uchio, S. C. Song, D. Mix, and S. W. Kim, Physical stability of insulin through chemical modification : site-specific glycosylation   and pegylation, Advanced Biomateials in  Biomedical Engineering and Drug Delivery Systems, 1996, 337

  • Y. H. Bae, S. W. Kim, A.  Kikuchi, S. J. Chong, and S. C. Song, Sulfonylurea grafted polymers for langerhans islets stimulation, ACS symp. Series, 1996, 627, 42

  • S. C. Song, T. Akaike, and K. Hatanaka, Gel Filtration fractionation of Cellulase from Trichoderma Viride and Its Application to  the Synthesis of the Branched Polysaccharide, Polymer J., 1994, 26, 387

  • K. Hatanaka, S. C. Song, A. Kukimiya, A. Maruyama, T. Akaike,  A. Kobayashi, and  H. Kuzuhara, Attempt to Control Sequence of Branched Polysaccharide with Enzymatic Hydrolysis and/or Copolymerization, Polymer J., 1993, 25, 373

  • K. Hatanaka, S. C. Song, A. Maruyama, and T. Akaike, Novel Synthetic Route Including Enzymatic Reaction for a Synthesis of a Branched   Polysaccharide, J. Carbohydr.   Chem, 1993, 11, 1027

  • K. Hatanaka, S. C. Song, A. Maruyama, and T. Akaike, A New Synthetic Hypoglycaemic Polysaccharide, Biochem. Biophys. Res. Commun., 1992, 188, 16

  • C. S. Cho,S. C. Song, M. Kunou, and T. Akaike, Orientation of Poly(γ-benzyl L-glutamate)/ poly(propylene oxide) triblock    Lanmuir-Blodgett Films by Circular Dichroism, J. Colloid Interface Sci., 1990, 137, 292

Patents

Poly(organophosphazene) containing degradation controllable ionic group, preparation method thereof and use thereof

Young-Min Kim, Soo-chang Song

KP (10-1480363)

 

Biodegradable and thermosensitive poly(phosphazene)-superparamagnetic nano-particle complex, preparation method and use thereof

Soo-chang Song, Jang-il Kim

KR (10-1209266), US (13/173,756), US (9017726)

 

Polyphosphazene composition for biomaterials

Soo-chang Song, Thrimoorthy Potta, Mi-Ran Park

KR (10-2010-0006000), US (13/173,783)

 

Poly(organophosphazene) hydrogels for drug delivery, preparation method thereof and use thereof

Soo-Chang Song, Sun Mi Lee, Mi-Ran Park

KR (10-0968591), PCT (PCT/KR2008/002715), US (12/122,665), EP (08753511.8)

 


Phosphazene hydrogels with chemical cross-link, preparation method thereof and use thereof

Soo-Chang Song, Thrimoorthy Potta, Sun Mi Lee

KR (2008-0040662), PCT (PCT/KR2008/002716), US (8313771), EP (2155806)

 

Thermosenstive polyphosphazene-bioactive molecules conjugates, preparation, method thereof and use thereof

Soo-Chang Song, Sun Mi Lee, Chang Won Kim

KR (1007469620000), PCT (PCT/KR2006/004574), US (11/568,852), JP (2009-504100), CHINA (200680054841.4),

INDIA (5527/CHENP/2008), EP (06812411.4)

 

Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof

Soo-Chang Song, Sun Mi Lee, Chang Won Kim, Mi-Ran Park

KR (1007844850000), PCT (PCT/KR2006/004573), US (11/568,851), CHINA (200680051281.7),

JP (2008-551170), EP (06812410.6), CANADA (2,637,285)

 

Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same

Soo-Chang Song, B. H Lee

KR (2005-517643), US (7259225), PCT (WO05/010079), EP (1654302), CANADA (2534268), JP (4145336),

CHINA (1829763), INDIA (427/KOLNP/2006)

 

Biodegradable and thermosensitive polyphosphazenes and their preparation method

Y. S. Sohn, Soo-Chang Song, S. B. Lee, B. H Lee

KR (2001-0047025), US (6319984), PCT (WO01/036516), EP (1161480), JP (3739706), SPAIN (2234562),

GERMANY (60016900), CANADA (2360557), CHINA (1145661)

 

Thermosensitive cyclotriphosphazene-platinum complex conjugate, its preparation method and anticancer agent containing the same

Y. S. Sohn, Soo-Chang Song, S. B. Lee

KR (363394), US (6333422), PCT (PCT/KR01/00033), EP (1311519), CHINA (1388808), JP (3677269),

CANADA (2388334), AUSTRALIA (781233)

 

Thermosensitive cyclotriphosphazene derivatives and a preparation method thereof

Y. S. Sohn, Soo-Chang Song, S. B. Lee

KR (2001-0045493), PCT (PCT/KR00/00043), US (6417383), EP (1140954), SPAIN (2202044),

ENGLAND (1140954), FRANCE (1140954), GERNANY (1140954)

 

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